KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYROXD1
All Species:
8.48
Human Site:
T281
Identified Species:
15.56
UniProt:
Q8WU10
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WU10
NP_079130.2
500
55793
T281
I
L
K
K
K
S
F
T
F
P
R
D
H
K
S
Chimpanzee
Pan troglodytes
XP_520786
500
55723
T281
I
L
K
K
K
S
F
T
F
P
G
D
H
K
S
Rhesus Macaque
Macaca mulatta
XP_001098386
500
55757
T281
I
L
K
K
K
S
F
T
F
P
R
D
P
K
S
Dog
Lupus familis
XP_534871
564
62639
P344
I
S
K
K
K
S
L
P
F
P
R
D
R
C
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3TMV7
498
55573
A278
I
M
K
K
K
S
L
A
F
P
K
D
H
H
K
Rat
Rattus norvegicus
Q68FS6
498
55471
A278
I
M
K
K
K
S
L
A
F
P
K
D
H
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507787
271
29578
V59
L
L
V
T
A
S
P
V
I
K
A
V
T
N
F
Chicken
Gallus gallus
XP_416422
500
55202
A281
Q
L
Q
Q
T
S
L
A
F
P
K
E
G
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBT5
490
54238
L271
Q
I
Y
T
Q
Q
E
L
L
Q
S
E
H
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610023
472
52333
D260
S
R
I
S
S
V
Q
D
L
A
D
D
A
G
A
Honey Bee
Apis mellifera
XP_624926
477
53873
Q265
K
I
L
N
K
S
E
Q
K
E
F
D
P
M
E
Nematode Worm
Caenorhab. elegans
NP_495754
451
50706
Q239
W
C
S
Q
I
D
F
Q
K
I
S
E
K
S
E
Sea Urchin
Strong. purpuratus
XP_782117
495
54197
V277
K
L
G
I
T
E
T
V
P
D
I
G
G
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.1
74.6
N.A.
85
85.1
N.A.
40.2
77
N.A.
64
N.A.
46.4
50
32.7
57.4
Protein Similarity:
100
99.5
98
81.2
N.A.
90.8
91.5
N.A.
44.4
86.8
N.A.
80.4
N.A.
62.2
66
54
72.2
P-Site Identity:
100
93.3
93.3
60
N.A.
60
60
N.A.
13.3
33.3
N.A.
6.6
N.A.
6.6
20
6.6
6.6
P-Site Similarity:
100
93.3
93.3
66.6
N.A.
73.3
73.3
N.A.
20
66.6
N.A.
33.3
N.A.
13.3
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
24
0
8
8
0
8
8
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
8
0
8
0
8
8
62
0
0
0
% D
% Glu:
0
0
0
0
0
8
16
0
0
8
0
24
0
0
16
% E
% Phe:
0
0
0
0
0
0
31
0
54
0
8
0
0
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
8
16
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
39
16
0
% H
% Ile:
47
16
8
8
8
0
0
0
8
8
8
0
0
0
0
% I
% Lys:
16
0
47
47
54
0
0
0
16
8
24
0
8
31
16
% K
% Leu:
8
47
8
0
0
0
31
8
16
0
0
0
0
0
0
% L
% Met:
0
16
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
16
% N
% Pro:
0
0
0
0
0
0
8
8
8
54
0
0
16
0
0
% P
% Gln:
16
0
8
16
8
8
8
16
0
8
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
24
0
8
0
0
% R
% Ser:
8
8
8
8
8
70
0
0
0
0
16
0
0
8
24
% S
% Thr:
0
0
0
16
16
0
8
24
0
0
0
0
8
0
16
% T
% Val:
0
0
8
0
0
8
0
16
0
0
0
8
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _